These results were of interest for investigaing the cytotoxicity of these plants against. Cytotoxicity of extracts from fruit plants against. Cytotoxic properties of some medicinal plant extracts from. Evaluation of the cytotoxic activity of extracts from medicinal plants. Pdf cytotoxic activity of a plant extract on cancer cells. Many of these plants, have therapeutic effects and can be extracted and used in preparation of drugs, used directly or in combination with other plant extracts for.
Pdf cytotoxic effects of bangladeshi medicinal plant extracts. Morus albamultiflora showed the highest cytotoxic effect on p19 cells which is. Conversely, the conventional chemotherapeutic drug showed a marked cytotoxicity on control cells. Cytotoxicity evaluation of methanol extracts of some medicinal. The plant extracts were screened for cytotoxicity, using the brine shrimp lethality assay bsla and mtt cytotoxicity assay.
However, our results in this study may predict that which species of leguminosae family will give better results on cancer cell lines. Table 2 shows the cytotoxic activity of the nine plant extracts that are commonly used in the treatment of cancer or cancer related illnesses in tanzanian traditional medicine. Table 3 shows the cytotoxic activity of the 38 plants that are commonly used in tanzanian traditional medicine to treat noncancer diseases. Plants are a significant reservoir of cytotoxic agents, including compounds with the ability to interfere with multidrugresistant mdr cells. In the present study, we report comparative data regarding the in vitro cytotoxic effect of different plant extracts on a panel of human tumor cell lines. Cocculus hirsutus, dpph, mtt assay, antioxidant, cytotoxicity. In vitro screening for cytotoxic activity of herbal extracts hindawi. Pdf to investigate the cytotoxic effect of some bangladeshi medicinal plant extracts, 16 bangladeshi medicinal plants were successively extracted with. The antibacterial activity of extracts of nine plant. Genotoxicity, cytotoxicity and toxicological evaluation of whole plant extracts of the medicinal plant phyllanthus niruri phyllanthaceae. With the aim of finding promising candidates for chemotherapy, 91 native and naturalized plants collected from the central region of argentina were screened for their cytotoxic effect toward sensitive and mdr pglycoprotein pgp overexpressing human. The antibacterial activity of extracts of nine plant species with good activity against escherichia coli against five other bacteria and cytotoxicity of extracts ishaku leo elisha 1.
Interestingly, mangosteen peel extract exhibited cytotoxicities against caco2 and pbmcs cells. Scientists collect different parts of many plants, prepare extracts, and test the extract for finding new and novel chemotherapeutics to treat cancer, as well as viral and microbial infection. Trypan blue exclusion assay and mtt assay were used for evaluation of plant extract cytotoxicity. Antioxidant activity of the plant extracts were characterized by using dpph free radical scavenging method. Evaluation of the cytotoxic activity of extracts from medicinal plants used for. Cytotoxic activity of extracts from plants of central. Materials and methods plant materials vitex trifolia study was collected from, west sudan, collected on february 2012. Brine shrimp lethality assay is a primary assay to detect cytotoxic property of plant extract and, further studies are required to establish the cytotoxicity of the plant extracts against human cancer cell lines. Trypan blue exclusion assay and mtt assay were used forcirchorium intybus evaluation of plant extract cytotoxicity. Cytotoxicity evaluation of methanol extracts of some.
Results and discussion calculation % cell viability a540 of treated cells a540 of control cells. Plants have been the traditional source of raw materials for medicines. The taxonomic identification of the plant was carried. Cytotoxicity of vitex trifolia leaf extracts on mcf7 and. Cytotoxic screening of plants is the preliminary methods to identify active compounds of plants 3, 4. Pomegranate peel had the highest antioxidative activity, followed by the extracts of rambutan, mangosteen, and banana peels. Antioxidant and in vitro cytotoxic activity of extracts of aerial parts of. Potential genotoxic and cytotoxic effects of plant extracts. Antioxidant and in vitro cytotoxic activity of extracts of. Cytotoxicity of some medicinal plant extracts used in. In vitro cytotoxic activity of medicinal plants from nigeria. Review cytotoxic studies of plant extracts cytotoxicity of plant extracts on both plant and animal test material is capturing scientific interest, as it can indicate their antitumor and anticarcinogenic potentials, which have always been a gateway for the development of novel anticancer drugs.
976 1041 169 1344 464 768 698 1560 1522 548 1003 334 213 775 580 1216 806 1229 738 1085 1531 1423 86 2 944 697 648 741 1130 445 316 649 1029 1105 336 921 28 240 40 794 267 618 728